What do the Frame Measurements mean?

The easiest way to get the right frame size is to get the dimensions from a comfortable pair of glasses you already have.

On one of the legs you will usually find (with the aid of a magnifying glass) three measurements, the first two separated by a rectangle.

glasses arms dimensions
glasses front dimensions
glasses profile dimensions

The Lens Diameter is a matter of choice, but the other two determine the fit.

They do not need to be exact, but the closer they are to your existing pair, the more likely your new glasses are to be a comfortable fit.